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- Bactofree is an antibiotic ointment used for treating certain skin infections, including impetigo and recurring boils. It effectively kills bacteria, alleviating symptoms and treating the underlying infection.
- Bactofree contains mupirocin, which inhibits bacterial protein synthesis by binding to isoleucyl transfer RNA synthetase. It is effective against both gram-positive and some gram-negative bacteria.
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✅ Description:
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Pharmacology
- Mechanism of Action: Mupirocin is a naturally occurring antibiotic produced by Pseudomonas fluorescens. It works by inhibiting bacterial protein synthesis through reversible binding to bacterial isoleucyl transfer-RNA synthetase.
- Spectrum of Activity: Effective against a wide range of bacteria, including:
- Gram-positive bacteria: Staphylococcus aureus (including MRSA) and Streptococcus pyogenes.
- Gram-negative bacteria: Escherichia coli and Haemophilus influenzae.
- Resistance: Due to its unique mechanism, mupirocin shows no cross-resistance with other antimicrobial agents and is bactericidal at topical concentrations.
✔️ Side Effects of Bactofree 2% Ointment
Common side effects may include:
- Application site reactions (burning, irritation, itching, redness).
- Rarely, systemic reactions (nausea, headache, dizziness, abdominal pain, allergic reactions).
Limited data is available on overdose. In case of an overdose, supportive treatment and monitoring are recommended.
✔️ Dosage & Administration of Bactofree 2% Ointment
- Apply a small amount of Bactofree ointment to the affected area 3 times daily for up to 10 days.
- Pediatric Use: Safety and effectiveness established for ages 2 months to 16 years through well-controlled studies.
Usage should be as per the advice of a registered medical practitioner.
✔️ Interactions
- No known drug interactions were identified with mupirocin ointment.
✔️ Contraindications
Contraindicated in individuals with a history of hypersensitivity to mupirocin or any of its components.
✔️ Pregnancy & Lactation
- Animal studies have shown no harm to the fetus; however, there is limited clinical experience during pregnancy. Use only if benefits outweigh risks.
- It is unknown if mupirocin is excreted in human milk, so caution is advised when administered to nursing mothers.
✔️ Precautions & Warnings
- Not for ophthalmic or intranasal use.
- Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.
- Avoid contact with the eyes, particularly when used on the face.
- Not suitable for use at the site of central venous cannulation or with cannulae.
- Discontinue use in case of severe local irritation or sensitization and consider alternative therapy.
- Do not mix with other preparations to avoid dilution and loss of antibacterial activity.
- Clean the area before applying Bactofree.
- If the condition does not improve within 3-5 days, consult your doctor.
- Store the ointment properly and follow all usage instructions for best results.
✔️ Storage Conditions
- Store below 25°C, protected from light and moisture.
- Do not freeze.
- Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
